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DARC-G4.0P专业版通用重力环境模拟系统 型号: DARC-G4.0P | 价格: 请联系我们详询,谢谢！
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| 标配多功能T25培养瓶适配器 | 可选配的SG-BSV球体反应器1350ml | 可选配的圆周阵适配器&SG-RWV |
产品概述
DARC-G通用重力环境模拟系统是第一台上市销售的国产二轴3D回转细胞培养系统，是首个采用可更换模块设计的二轴3D回转细胞培养系统。针对DARC-G通用重力环境模拟系统，我们开发了数十款不同适配器、生物反应容器以满足不同场景的需求，帮助用户更便捷、更高效地开展各种科研实验。DARC-G通用重力环境模拟系统配合不同模块可用于基于微重力、超重力环境下的生命科学、材料科学、新能源等研究工作。DARC-G通用重力环境模拟系统可提供0.001-6g的重力模拟水平。
1770年到19世纪的一百多年的时间里，各国科学家进行了大量的气球载人、载动物的升空试验。当时人们没有认识高空环境会对人体带来危害，没有采取相应的保护措施，以致在升空中发生了人的冻伤、耳痛、意识丧失甚至死亡的严重事故。此后人们便重视和开展高空环境的研究，逐渐认识到低压、缺氧、低温对体的危害，这是航空医学的萌芽时期。飞机的制造、飞行是19世纪末20世纪初实现的。当时飞机的性能较低，航行高度仅两千米，飞行速度也仅有每小时500公里。即使这样也发生了晕机、着陆事故、飞机碰撞等急待解决的问题。第二次世界大战期间，特别是喷气飞机出现后，飞机的性能提高，航行高度增高，速度增快，续航时间延长，出现了由超重、低压、缺氧、低温等引起的医学问题，这迫使各国投入了大量人力物力用于开展航空医学研究。航天医学是在航空医学基础上发展的。40年代末50年代初，人们进行了广泛的火箭和卫星的生物学试验。动物实验证明人类可以到宇宙航行后，苏联在60年代初首先载人航天成功。随后研究了人在宇宙飞行的安全返回、失重对人体的影响等，证明人可以在失重条件下有效地工作和健康地生活。随着航天技术的发展，航天医学也相应地迅速发展。
航天器发射和返回时同样产生时间较长的加速、减速超重，超重值可达6G左右。高G值的超重，人取坐姿难以适应，所以航天员通常采取仰卧姿，这对人体的影响较轻。人对6G值的横向超重可耐受十多分钟。航天中经受的这种横向超重，一般人都可以耐受。飞行中各种加速度对人体的前庭器官是一种刺激，在适宜范围内一般不会引起不良反应，当加速度刺激频繁、剧烈，时间较长，超过前庭器官的阈值，即可引起运动病反应。运动病有晕船、晕机、晕车、航天运动病等。主要症状是头晕、恶心、呕吐、出冷汗、面色苍白等。病因与前庭器官密切相关，丧失前庭功能的聋哑人前庭器官发育不全的人，一般不会发生运动病。军事飞行中乘员晕机的较多。民航客机飞行平稳，座舱舒适，发生晕机的旅客一般不超过6%。
失重是航天飞行中的一个特殊物理因素。人体的结构特点，保证人对重力的对抗和适应。载人航天实践证明，失重对人体的生理功能有很大影响，但不像原先想象的那样严重。人在失重条件下连续生活工作365天后，返回地球经短期休息，可完全地恢复健康，并未发生不可逆转的生理变化。随着空间探索的兴起，尤其是我国近年在空间飞行、探索上所取得的成绩 ——空间站的建成，让原本很多只是停留的理论上、文献中的一些猜想得以在真实的环境下进行验证。然而，现有资源仍然是有限的，因此，如果能够在地面开展一些模拟场景下的研究，就显得十分必要。在这方面，欧美等发达国家早已走在前列，比如欧洲空客公司开发的RPM随机定位仪、美国NASA开发的RCCS旋转培养系统等等，都有超过20年以上历史，基于这些模拟平台开展的科研项目众多。DARC-G系列通用重力环境模拟系统，是国内首个面向市场的商业化微重力、超重力模拟平台，并且也是全球首个采用模块化设计的平台，比如配套的SG-BSV球形（球釜）反应容器。借助于该系统，用户可以在地面实验室开展多种基于模拟微重力、超重力环境下的生物、材料、流体等方面的实验。
The DARC-G Universal Gravity Environment Simulation System is the first domestic two-axis 3D rotating cell culture system available on the market. It is also the first two-axis 3D rotating cell culture system adopting a replaceable module design. For this system, we have developed dozens of different adapters and bioreaction vessels to meet the needs of various scenarios, helping users conduct various scientific research experiments more conveniently and efficiently. Equipped with different modules, the DARC-G can be used for research in life sciences, materials science, new energy and other fields under microgravity and hypergravity environments. It can provide a gravity simulation range of 0.001-6g.
Development of Aerospace and Space Medicine
From 1770 to the 19th century, a period of over a hundred years, scientists from various countries conducted numerous balloon experiments carrying humans and animals into the air. At that time, people did not realize the hazards of the high-altitude environment to the human body and failed to take corresponding protective measures. This led to serious accidents during ascents, such as frostbite, ear pain, loss of consciousness and even death of personnel. Afterwards, people began to attach importance to and carry out research on the high-altitude environment, gradually recognizing the hazards of low pressure, hypoxia and low temperature to the human body. This marked the embryonic stage of aerospace medicine.
The manufacture and flight of aircraft were realized in the late 19th and early 20th centuries. At that time, aircraft performance was relatively low, with a cruising altitude of only 2,000 meters and a flight speed of just 500 kilometers per hour. Even so, problems such as motion sickness, landing accidents and aircraft collisions emerged, which urgently needed to be solved. During World War II, especially after the emergence of jet aircraft, aircraft performance improved significantly—with increased cruising altitude, speed and endurance. Medical issues caused by hypergravity, low pressure, hypoxia, low temperature and other factors arose, forcing countries to invest a large amount of manpower and material resources in aerospace medicine research.
Space medicine developed on the basis of aerospace medicine. In the late 1940s and early 1950s, extensive biological experiments on rockets and satellites were carried out. After animal experiments proved that humans could travel in space, the Soviet Union first achieved successful manned spaceflight in the early 1960s. Subsequent research focused on the safe return of humans from spaceflight and the impact of weightlessness on the human body, confirming that humans could work effectively and live healthily under weightless conditions. With the development of space technology, space medicine has also advanced rapidly.
During the launch and return of spacecraft, prolonged acceleration and deceleration hypergravity are generated, with hypergravity values reaching around 6G. Humans find it difficult to adapt to high-G hypergravity in a sitting position, so astronauts usually adopt a supine posture, which has a milder impact on the human body. Humans can tolerate transverse hypergravity of 6G for more than ten minutes. This type of transverse hypergravity experienced in spaceflight is tolerable for most people.
Various accelerations during flight stimulate the human vestibular organs. Within an appropriate range, they generally do not cause adverse reactions. However, when the acceleration stimulation is frequent, intense and prolonged beyond the threshold of the vestibular organs, motion sickness may occur. Motion sickness includes seasickness, airsickness, carsickness, space motion sickness, etc. Its main symptoms are dizziness, nausea, vomiting, cold sweats, pale complexion and so on. The cause is closely related to the vestibular organs. Deaf-mutes with lost vestibular function and people with underdeveloped vestibular organs generally do not suffer from motion sickness. Airsickness is relatively common among crew members in military flights. Civil aviation airliners fly smoothly with comfortable cabins, and airsickness affects no more than 6% of passengers.
Weightlessness is a special physical factor in spaceflight. The structural characteristics of the human body enable it to resist and adapt to gravity. Manned spaceflight practice has proved that weightlessness has a significant impact on human physiological functions, but not as severe as originally imagined. After living and working continuously under weightless conditions for 365 days, humans can fully recover their health after a short rest upon returning to Earth, with no irreversible physiological changes.
With the rise of space exploration, especially China's recent achievements in spaceflight and exploration—such as the completion of the space station—many hypotheses that were previously only theoretical or documented have been verified in real environments. However, existing resources are still limited. Therefore, it is very necessary to carry out research under simulated scenarios on the ground. In this regard, developed countries such as Europe and the United States have long been at the forefront. For example, the RPM (Random Positioning Machine) developed by Airbus in Europe and the RCCS (Rotary Cell Culture System) developed by NASA in the United States have a history of more than 20 years, and numerous scientific research projects have been carried out based on these simulation platforms.
The DARC-G series Universal Gravity Environment Simulation System is China's first commercial microgravity and hypergravity simulation platform for the market, and also the world's first platform adopting a modular design—such as the supporting SG-BSV spherical (ball kettle) bioreaction vessel. With this system, users can conduct various experiments on biology, materials, fluids and other fields under simulated microgravity and hypergravity environments in ground laboratories.
优势介绍
DARC-G4.0P 通用重力环境模拟系统在技术创新与应用适配性上展现出显著优势，其核心竞争力主要表现在以下几个方面The DARC-G4.0P Universal Gravity Environment Simulation System demonstrates significant advantages in technological innovation and application adaptability, with its core competitiveness mainly reflected in the following aspects：
一、全维度重力覆盖与高精度调控Full-Dimensional Gravity Coverage and High-Precision Regulation
DARC-G4.0P 系统支持 0.001-6g 超宽重力范围调节，覆盖从微重力0.001g（含月球 0.16g、火星 0.38g）到超重力（航天器发射阶段 6g）的全场景需求。其重力调节精度达 0.0005g，转速控制范围 0-30RPM，通过二轴随机回转运动实现三维空间动态平衡，较传统单轴系统（如 Synthecon RCCS）的一维运动更贴近太空真实环境。
The DARC-G4.0P system supports ultra-wide gravity range adjustment of 0.001-6g, covering all scenario needs from microgravity (0.001g, including lunar gravity 0.16g and Martian gravity 0.38g) to hypergravity (6g during spacecraft launch phase). It achieves a gravity adjustment precision of 0.0005g and a rotational speed control range of 0-30RPM. Through two-axis random rotation, it realizes three-dimensional spatial dynamic balance, which is closer to the real space environment than the one-dimensional motion of traditional single-axis systems.
二、模块化设计与通用兼容性Modular Design and Universal Compatibility
DARC-G4.0P 作为全球首款采用可更换模块化设计的商用系统，其可切换模块支持 16 只 T25 培养瓶、22 只 SG-RWV 旋转壁反应容器或 1350ml BV 球釜的灵活组合，培养容量较同类产品提升 数十倍，模块更换成本降低 50%。区别于进口设备依赖专用耗材的局限，该系统兼容通用培养皿、生物反应器等容器，可无缝对接实验室现有设备，显著降低使用成本。
三、高通量与多模式同步实验能力High-Throughput and Multi-Mode Simultaneous Experiment Capability
DARC-G4.0P 系统支持 22 只旋转壁反应容器或 16 只 T25 培养瓶的高通量实验，结合预置的多种微重力模式（如抛物线、随机定位）及 8 种超重力模式（如恒定离心、脉冲加载），可同步开展多组对比实验，科研效率大幅提升。其模块化设计还支持从细胞生物学、肿瘤研究到航天医学的跨学科应用，突破传统设备的单一领域限制。The DARC-G4.0P system supports high-throughput experiments with 22 rotating wall vessels or 16 T25 culture flasks. Combined with preset multiple microgravity modes (e.g., parabolic, random positioning) and 8 hypergravity modes (e.g., constant centrifugation, pulse loading), it can simultaneously conduct multiple groups of comparative experiments, greatly improving scientific research efficiency. Its modular design also supports interdisciplinary applications from cell biology and tumor research to aerospace medicine, breaking the single-field limitation of traditional equipment.
四、超重力应用场景的颠覆性突破Subversive Breakthrough in Hypergravity Application Scenarios
DARC-G4.0P 设备体积仅为国际同类产品体积的2/3，这种技术突破不仅显著降低工业能耗，更将设备小型化与移动化变为可能，为极端环境下的处理提供新方案。The volume of the DARC-G4.0P equipment is only 2/3 that of international similar products. This technological breakthrough not only significantly reduces industrial energy consumption but also makes equipment miniaturization and mobility possible, providing a new solution for processing under extreme environments.
五、微重力模拟的生物医学创新Biomedical Innovation in Microgravity Simulation
DARC-G4.0P 通过二轴随机回转运动模拟太空无沉降环境，系统实现 100% 无气泡动态悬浮培养，使三维组织构建均一性提升 30%，代谢效率显著优化。例如，间充质干细胞在微重力下向软骨细胞分化效率提升 30%，成骨细胞矿化结节形成效率提高，为骨与软骨再生研究提供理想平台。Through two-axis random rotation, the DARC-G4.0P simulates the sedimentation-free space environment. The system achieves 100% bubble-free dynamic suspension culture, increasing the uniformity of three-dimensional tissue construction by 30% and significantly optimizing metabolic efficiency. For example, the differentiation efficiency of mesenchymal stem cells into chondrocytes under microgravity is increased by 30%, and the formation efficiency of osteoblast mineralized nodules is improved, providing an ideal platform for bone and cartilage regeneration research.
六、跨学科科研的集成化平台Integrated Platform for Interdisciplinary Scientific Research
DARC-G4.0P 系统整合生命科学与工程技术应用，这种跨学科兼容性使其成为连接航天前沿与生物医药创新的关键纽带。The DARC-G4.0P system integrates life science and engineering technology applications. This interdisciplinary compatibility makes it a key link connecting aerospace frontiers and biomedicine innovation.
七、经济性与国产化技术突破Economy and Domestic Technological Breakthrough
DARC-G4.0P 作为国产自主创新产品，其价格低于进口设备，同时提供定制化服务与全周期技术支持，显著降低科研机构长期使用成本。例如，其旋转细胞培养系统适配多种容器类型，避免了进口设备专用耗材的高昂支出，且模块更换成本仅为国际同类产品的 50%。As a domestically independent innovative product, the DARC-G4.0P is priced lower than imported equipment. It also provides customized services and full-cycle technical support, significantly reducing the long-term usage costs of scientific research institutions. For example, its rotating cell culture system is compatible with various container types, avoiding the high expenditure on dedicated consumables for imported equipment, and the module replacement cost is only 50% of that of international similar products.
八、航天医学研究的精准模拟Accurate Simulation for Aerospace Medicine Research
DARC-G4.0P 系统支持一键模拟月球、火星重力环境，结合 22 只旋转壁反应容器的高通量能力，可同步开展多组对比实验，例如模拟宇航员骨流失机制时，其 “体外组织库” 构建效率较传统方法提升 50%。这种精准模拟能力为长期太空驻留任务中的组织修复提供了关键技术支撑。The DARC-G4.0P system supports one-click simulation of lunar and Martian gravity environments. Combined with the high-throughput capability of 22 rotating wall vessels, it can simultaneously conduct multiple groups of comparative experiments. For instance, when simulating astronauts' bone loss mechanisms, the construction efficiency of its "in vitro tissue bank" is 50% higher than traditional methods. This accurate simulation capability provides key technical support for tissue repair during long-term space residency missions.
九、工业化生产的规模化潜力Large-Scale Potential for Industrial Production
DARC-G4.0P 通过 1350ml 大容量培养容器，系统突破地面三维构建瓶颈，可规模化制备高活性角膜、软骨等组织移植物，其单次培养量较传统设备提升显著。在超重力反应结晶技术中，碳酸钙纳米颗粒的粒径分布均匀性提升明显，反应时间从数小时缩短至分钟级，显著优化化工工艺效率。With a 1350ml large-capacity culture container, the DARC-G4.0P system breaks through the bottleneck of ground-based three-dimensional construction, enabling large-scale preparation of high-activity tissue grafts such as corneas and cartilage. Its single-culture volume is significantly higher than that of traditional equipment. In hypergravity reaction crystallization technology, the particle size distribution uniformity of calcium carbonate nanoparticles is significantly improved, and the reaction time is shortened from several hours to minutes, greatly optimizing chemical process efficiency.
DARC-G4.0P 系统通过二轴随机回转运动、转角实时控制、模块化设计与宽范围重力调控、完整的胚胎适配器及专用生物反应容器、类器官芯片的的有机结合，在微重力组织构建、微重力类器官构建、超重力材料合成、航天医学模拟等领域展现出多项优势。Through the organic combination of two-axis random rotation, real-time rotation angle control, modular design, wide-range gravity regulation, complete embryo adapters, dedicated bioreaction vessels, and organoid chips, the DARC-G4.0P system demonstrates multiple advantages in fields such as microgravity tissue construction, microgravity organoid formation, hypergravity material synthesis, and aerospace medicine simulation.
应用场景
DARC-G4.0P 通用重力环境模拟系统（微重力 & 超重力）是一款集高精度调控与多场景适配于一体的科研设备，通过 0.001-6g 重力范围调节及 0-30RPM 转速控制，结合真动态 3D 回转技术与数款适配器可切换模块，为生命科学、材料工程及航天医学等领域提供全维度研究平台。其应用场景可分为两大核心方向（但不限于以下场景）：
该系统通过预置多种微重力模式（如抛物线、随机定位）及 8 种超重力模式（如恒定离心、脉冲加载），结合 22 只旋转壁反应容器或 16 只 T25 培养瓶的高通量能力，可同步开展多组对比实验，显著提升科研效率。其模块化设计支持从细胞生物学、肿瘤研究到航天医学的跨学科应用，为揭示重力环境下的生命现象与物质规律提供了理想平台。
常见问答
1、DARC-G4.0P 通用重力环境模拟系统可以同时模拟微重力、超重力吗？
答：DARC-G4.0P 通用重力环境模拟系统具备微重力模拟（最小0.001g）和超重力模拟（最大6g）两种重力环境模拟功能能；
2、DARC-G4.0P通用重力环境模拟系统属于医疗设备吗，有医疗器械注册许可证吗？
答：尽管目前已经有相关研究将一些疾病模型引入微重力环境下进行，但DARC-G4.0P 通用重力环境模拟系统主要被设计用于科研领域，不属于医疗器械，无需医疗器械注册许可证；
3、DARC-G4.0P 通用重力环境模拟系统符合GMP和GLP法规吗？
答：DARC-G4.0P 通用重力环境模拟系统在设计、制造过程中参考了相关的GMP和GLP法规要求，如用户权限分级管理、数据防篡改或追踪；
4、DARC-G4.0P 通用重力环境模拟系统可以提供3Q验证报告吗？
答：标准设备不提供3Q验证报告，但如果用户有这方面需求，我们可以有偿提供3Q验证报告，包括年度3Q验证服务，具体请与我司销售人员联系咨询；
5、DARC-G4.0P 通用重力环境模拟系统除了做微重力细胞或超重力细胞培养外还可以用于哪些研究？
答：该系统不仅适用于细胞培养，也适用于组织或类器官，并且适用于植物组织的微重力或超重力研究，以及适用于如斑马鱼胚胎、成鱼、果蝇等，此外，一些定制机型还可以支持高低温环境（比如DARC-G4.0H 提供了室温至250度高温环境下的微重力、超重力模拟功能）；
6、DARC-G4.0P 通用重力环境模拟系统可以用来支持培养液连续更新吗？
答：DARC-G4.0P 通用重力环境模拟系统不支持培养液连续更新，但如果有这方面需求可以选用我司其它型号，比如DARC-P2.0S 灌流重力环境模拟培养系统，这款支持培养液连续自动更新；
7、DARC-G4.0P 通用重力环境模拟系统能够提供ISO9001或者ISO13485认证吗？
答：目前我司正在积极开展相关ISO系列认证，预计2026年下半年可以提供相关ISO认证证书；
8、DARC-G4.0P 通用重力环境模拟系统拥有相关技术专利吗，是自主产品吗？
答：我司目前所销售的产品几乎都有自主专利，包括DARC系列以及SARC系列等产品；
9、DARC-G4.0P 通用重力环境模拟系统兼容贵司的多种培养耗材吗，比如SG-RWV旋转壁反应容器、SG-BSV球体反应容器、SG-NSV零剪切力反应容器等？
答：我司所有开发的培养耗材充分考虑了现有产品及用户的利益诉求，力争能够适配所有现有产品（除非在功能上存在不可兼容的特性），上面提到的SG系列培养耗材/反应容器均可以在DARC-G4.0P上使用。
关键字: 微重力模拟,超重力模拟,微重力细胞培养,超重力细胞培养,微重力类器官,微重力器官,超重力类器官,超重力器官,微重力干细胞培养
